Bad Can Act as a Key Regulator of  T Cell Apoptosis and T Cell Development

Bad is a distant relative of Bcl-2 and acts to promote cell death. Here, we show that Bad expression levels are greatly increased in thymocytes during apoptosis. We generated bad transgenic mice to study the action of upregulated Bad expression on T cell apoptosis. The T cells from these mice are hi...

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Detaylı Bibliyografya
Asıl Yazarlar: Mok, Chen-Lang, Gil-Gómez, Gabriel, Williams, Owen, Coles, Mark, Taga, Samir, Tolaini, Mauro, Norton, Trisha, Kioussis, Dimitris, Brady, Hugh J.M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 1999
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192908/
https://ncbi.nlm.nih.gov/pubmed/9927519
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