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Influence of antigen dose and costimulation on the primary response of CD8+ T cells in vitro

The influence of costimulation on the primary response of CD8+ T cells to class I alloantigens was studied with the aid of a T cell receptor transgenic model and defined peptides as antigen. With small doses of antigen, the proliferative response of CD8+ cells was high early in culture but was of br...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192558/
https://ncbi.nlm.nih.gov/pubmed/8642334
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