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Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab
BACKGROUND: Clinical targeting of TNFR family of receptors (CD40, CD134 and CD137) with immunostimulatory monoclonal antibodies has been successful in cancer immunotherapy. However, targeting of CD27 with a mAb is a relatively new approach to provide costimulation of immune cells undergoing activati...
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| Publicado no: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619281/ https://ncbi.nlm.nih.gov/pubmed/26500773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-015-0080-2 |
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