A carregar...
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
The CD45 transmembrane glycoprotein has been shown to be a protein phosphotyrosine phosphatase and to be important in signal transduction in T and B lymphocytes. We have employed gene targeting to create a strain of transgenic mice that completely lacks expression of all isoforms of CD45. The spleen...
Na minha lista:
| Formato: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1996
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192485/ https://ncbi.nlm.nih.gov/pubmed/8666928 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|