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CD45 enhances positive selection and is expressed at a high level in large, cycling, positively selected CD4+CD8+ thymocytes.

T-cell development is arrested at the CD4+CD8+ (DP; double-positive) stage of thymocyte development in CD45 null mice. However, the mechanism by which CD45 participates in the positive selection of T cells remains to be investigated. In this report we describe a DP thymocyte population that associat...

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Bibliografske podrobnosti
Main Authors: Ong, C J, Dutz, J P, Chui, D, Teh, H S, Marth, J D
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364040/
https://ncbi.nlm.nih.gov/pubmed/9203971
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