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Exploring the sequence space of a DNA aptamer using microarrays
The relationship between sequence and binding properties of an aptamer for immunoglobulin E (IgE) was investigated using custom DNA microarrays. Single, double and some triple mutations of the aptamer sequence were created to evaluate the importance of specific base composition on aptamer binding. T...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2190713/ https://ncbi.nlm.nih.gov/pubmed/17981839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm922 |
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