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Exploring the sequence space of a DNA aptamer using microarrays
The relationship between sequence and binding properties of an aptamer for immunoglobulin E (IgE) was investigated using custom DNA microarrays. Single, double and some triple mutations of the aptamer sequence were created to evaluate the importance of specific base composition on aptamer binding. T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2190713/ https://ncbi.nlm.nih.gov/pubmed/17981839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm922 |
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