Wordt geladen...

Active site binding and sequence requirements for inhibition of HIV-1 reverse transcriptase by the RT1 family of single-stranded DNA aptamers

Nucleic acid aptamers can potentially be developed as broad-spectrum antiviral agents. Single-stranded DNA (ssDNA) aptamer RT1t49 inhibits reverse transcriptases (RT) from HIV-1 and diverse lentiviral subtypes with low nanomolar values of Kd and IC(50). To dissect the structural requirements for inh...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Kissel, Jay D., Held, Daniel M., Hardy, Richard W., Burke, Donald H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976467/
https://ncbi.nlm.nih.gov/pubmed/17644816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm420
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!