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Exploring the sequence space of a DNA aptamer using microarrays

The relationship between sequence and binding properties of an aptamer for immunoglobulin E (IgE) was investigated using custom DNA microarrays. Single, double and some triple mutations of the aptamer sequence were created to evaluate the importance of specific base composition on aptamer binding. T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Katilius, Evaldas, Flores, Carole, Woodbury, Neal W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190713/
https://ncbi.nlm.nih.gov/pubmed/17981839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm922
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