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DNA replication stress, genome instability and aging

Genome instability is a fundamentally important component of aging in all eukaryotes. How age-related genome instability occurs remains unclear. The free radical theory of aging posits oxidative damage to DNA and other cellular constituents as a primary determinant of aging. More recent versions of...

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Bibliographic Details
Main Authors: Burhans, William C., Weinberger, Martin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190710/
https://ncbi.nlm.nih.gov/pubmed/18055498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1059
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