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Retrotransposition is associated with genome instability during chronological aging

Genetic damage through mutations and genome rearrangements has been hypothesized to contribute to aging. The specific mechanisms responsible for age-induced increases in mutation and chromosome rearrangement frequencies and a potential causative role for DNA damage in aging are under active investig...

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Bibliographic Details
Main Authors: Maxwell, Patrick H., Burhans, William C., Curcio, M. Joan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251071/
https://ncbi.nlm.nih.gov/pubmed/22021441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100271108
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