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Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

Long interspersed element-1 (L1) retrotransposons compose ∼20% of the mammalian genome, and ongoing L1 retrotransposition events can impact genetic diversity by various mechanisms. Previous studies have demonstrated that endogenous L1 retrotransposition can occur in the germ line and during early em...

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Main Authors: Coufal, Nicole G., Garcia-Perez, Josè Luis, Peng, Grace E., Marchetto, Maria C. N., Muotri, Alysson R., Mu, Yangling, Carson, Christian T., Macia, Angela, Moran, John V., Gage, Fred H.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251057/
https://ncbi.nlm.nih.gov/pubmed/22159035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100273108
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