Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

Long interspersed element-1 (L1) retrotransposons compose ∼20% of the mammalian genome, and ongoing L1 retrotransposition events can impact genetic diversity by various mechanisms. Previous studies have demonstrated that endogenous L1 retrotransposition can occur in the germ line and during early em...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Coufal, Nicole G., Garcia-Perez, Josè Luis, Peng, Grace E., Marchetto, Maria C. N., Muotri, Alysson R., Mu, Yangling, Carson, Christian T., Macia, Angela, Moran, John V., Gage, Fred H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Telomerase and Retrotransposons: Reverse Transcriptases That Shaped Genomes Special Feature Sackler Colloquium
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251057/
https://ncbi.nlm.nih.gov/pubmed/22159035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100273108
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