Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

Micro RNAs (miRNA) regulate gene expression by hybridization and recruitment of multi-protein complexes to complementary mRNA target sequences. miRNA function can transiently be antagonized by antagomirs—chemically modified oligonucleotides complementary to individual miRNAs. Here, we describe the i...

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Autors principals: Scherr, Michaela, Venturini, Letizia, Battmer, Karin, Schaller-Schoenitz, Michael, Schaefer, Daniel, Dallmann, Iris, Ganser, Arnold, Eder, Matthias
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190705/
https://ncbi.nlm.nih.gov/pubmed/18025036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm971
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