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Lentivirus-mediated antagomir expression for specific inhibition of miRNA function
Micro RNAs (miRNA) regulate gene expression by hybridization and recruitment of multi-protein complexes to complementary mRNA target sequences. miRNA function can transiently be antagonized by antagomirs—chemically modified oligonucleotides complementary to individual miRNAs. Here, we describe the i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2190705/ https://ncbi.nlm.nih.gov/pubmed/18025036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm971 |
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