miR-125b regulates chemotaxis and survival of bone marrow derived granulocytes in vitro and in vivo

The evolutionary conserved miR-125b is highly expressed in hematopoietic stem cells (HSC) enhancing self-renewal and survival. Accordingly, over-expression of miR-125b in HSC may induce myeloproliferative neoplasms and leukemia with long latency. During hematopoietic cell maturation miR-125b express...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Lee, Chun-Wei, Schoenherr, Caroline, Battmer, Karin, Ganser, Arnold, Hilfiker-Kleiner, Denise, David, Sascha, Eder, Matthias, Scherr, Michaela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171867/
https://ncbi.nlm.nih.gov/pubmed/30286140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204942
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