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Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis

The Rho GTPase Cdc42 regulates adhesion, migration, and homing, as well as cell cycle progression, of hematopoietic stem cells, but its role in multilineage blood development remains unclear. We report here that inducible deletion of cdc42 in cdc42-floxed mouse bone marrow by the interferon-responsi...

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Autors principals: Yang, Linda, Wang, Lei, Kalfa, Theodosia A., Cancelas, Jose A., Shang, Xun, Pushkaran, Suvarnamala, Mo, Jun, Williams, David A., Zheng, Yi
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190607/
https://ncbi.nlm.nih.gov/pubmed/17702896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-079582
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