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Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment

Rho family GTPases are key signal transducers in cell regulation. Although a body of literature has implicated the Rho family members Rac1 and Rac2 in multiple hematopoietic-cell functions, the role of Cdc42 in hematopoiesis remains unclear. Here we have examined the hematopoietic properties and the...

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Autors principals: Wang, Lei, Yang, Linda, Filippi, Marie-Dominique, Williams, David A., Zheng, Yi
Format: Artigo
Idioma:Inglês
Publicat: © 2006 by The American Society of Hematology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895350/
https://ncbi.nlm.nih.gov/pubmed/16174757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-2171
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