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Gene Targeting of Cdc42 and Cdc42GAP Affirms the Critical Involvement of Cdc42 in Filopodia Induction, Directed Migration, and Proliferation in Primary Mouse Embryonic Fibroblasts

Recent studies in Cdc42 knockout mouse embryonic stem (ES) cells and ES-derived fibroblastoid cell lines raise concern on a body of literature derived by dominant mutant expression approach in a variety of cell lines implicating mammalian Cdc42 as a key regulator of filopodia induction, directional...

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Bibliografische gegevens
Hoofdauteurs: Yang, Linda, Wang, Lei, Zheng, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635400/
https://ncbi.nlm.nih.gov/pubmed/16914516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0466
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