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Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction

The formation of a local zone of Cdc42 GTPase activity, which governs cell polarization in many cell types, requires not only local activation but also switch-off mechanisms. In this study, we identify Rga3, a paralog of Rga4, as a novel Cdc42 GTPase-activating protein (GAP) in the fission yeast Sch...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Gallo Castro, Daniela, Martin, Sophie G.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279383/
https://ncbi.nlm.nih.gov/pubmed/30279276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201806016
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