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Synthesis of C-4 and C-7 Triazole Analogs of Zanamivir as Multivalent Sialic Acid Containing Scaffolds

The relative reactivities of C-4 and C-7 azides derived from zanamivir were compared in cycloadition reactions with a panel of alkynes. All of the reactions proceeded efficiently with no observable differences between primary and secondary azides. Significant rate differences were observed between s...

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Detalhes bibliográficos
Main Authors: Lu, Yan, Gervay-Hague, Jacquelyn
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190540/
https://ncbi.nlm.nih.gov/pubmed/17597592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2007.06.002
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