Φορτώνει......
Synthesis of sulfone-based nucleotide isosteres: identification of CMP-sialic acid synthetase inhibitors
A modular replacement approach to the synthesis of sulfonucleotide analogs prepared from condensation of nucleoside aldehydes with bis phosphonate Horner-Wadsworth-Emmons reagents is disclosed. These analogs were shown to be inhibitors of Neisseria meningitidis CSS (NmCSS), which is a key enzyme in...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Org Biomol Chem |
|---|---|
| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505548/ https://ncbi.nlm.nih.gov/pubmed/19081938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b819155g |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|