Disordered Pancreatic Inflammatory Responses and Inhibition of Fibrosis in CD39-null mice

BACKGROUND & AIMS: Extracellular nucleotides are released from injured cells and bind to purinergic-type 2 receptors (P2-R) that modulate inflammatory responses. Ectonucleotidases, such as CD39/NTPDase1, hydrolyze extracellular nucleotides to integrate purinergic signaling responses. As the role...

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Hauptverfasser: Künzli, Beat M., Nuhn, Philipp, Enjyoji, Keiichi, Banz, Yara, Smith, Rex N., Csizmadia, Eva, Schuppan, Detlef, Berberat, Pascal O., Friess, Helmut, Robson, Simon C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189558/
https://ncbi.nlm.nih.gov/pubmed/18036594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.10.030
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