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Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer

Despite improvements in prevention and management of colorectal cancer (CRC), uncontrolled tumor growth with metastatic spread to distant organs remains an important clinical concern. Genetic deletion of CD39, the dominant vascular and immune cell ectonucleotidase, has been shown to delay tumor grow...

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Bibliographic Details
Main Authors: Künzli, Beat M., Bernlochner, Maria-Isabell, Rath, Stephan, Käser, Samuel, Csizmadia, Eva, Enjyoji, Keiichi, Cowan, Peter, d’Apice, Anthony, Dwyer, Karen, Rosenberg, Robert, Perren, Aurel, Friess, Helmut, Maurer, Christoph A., Robson, Simon C.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146639/
https://ncbi.nlm.nih.gov/pubmed/21484085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9228-9
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