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Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice

Sera from individual MRL/lpr and MRL/++ mice, which develop an autoimmune disease similar to human systemic lupus erythematosus (SLE), were screened over a period of approximately 30 wk for the presence of anti-RNA polymerase I and anti-ssDNA antibodies. Even though onset of the disease is delayed i...

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Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1985
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187993/
https://ncbi.nlm.nih.gov/pubmed/3877777
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