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Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages

In the current study, we show that macrophages adaptively resist anthrax lethal toxin (LT) through a toxin-activated process termed toxin-induced resistance (TIR). TIR was triggered by pretreatment of RAW 264.7 or J774A.1 macrophages with a low dose of LT for at least 6 h, which resulted in resistan...

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Autori principali: Salles, Isabelle I., Tucker, Amy E., Voth, Daniel E., Ballard, Jimmy D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC218774/
https://ncbi.nlm.nih.gov/pubmed/14519843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2134042100
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