Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus anthracis Survival

Alveolar macrophages (AM) are very important for pulmonary innate immune responses against invading inhaled pathogens because they directly kill the organisms and initiate a cascade of innate and adaptive immune responses. Although several factors contribute to inhalational anthrax, we hypothesized...

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Autors principals: Ribot, Wilson J., Panchal, Rekha G., Brittingham, Katherine C., Ruthel, Gordon, Kenny, Tara A., Lane, Douglas, Curry, Bob, Hoover, Timothy A., Friedlander, Arthur M., Bavari, Sina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594833/
https://ncbi.nlm.nih.gov/pubmed/16926394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00275-06
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