Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus anthracis Survival

Alveolar macrophages (AM) are very important for pulmonary innate immune responses against invading inhaled pathogens because they directly kill the organisms and initiate a cascade of innate and adaptive immune responses. Although several factors contribute to inhalational anthrax, we hypothesized...

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Main Authors: Ribot, Wilson J., Panchal, Rekha G., Brittingham, Katherine C., Ruthel, Gordon, Kenny, Tara A., Lane, Douglas, Curry, Bob, Hoover, Timothy A., Friedlander, Arthur M., Bavari, Sina
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594833/
https://ncbi.nlm.nih.gov/pubmed/16926394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00275-06
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