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Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway

Y box-binding protein 1 (YB-1) is a multifunctional protein that can act as a regulator of transcription and of translation. In chicken embryo fibroblasts transformed by the oncoproteins P3k (phosphatidylinositol 3-kinase) or Akt, YB-1 is transcriptionally down-regulated. Expression of YB-1 from a r...

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Hlavní autoři: Bader, Andreas G., Felts, Katherine A., Jiang, Ning, Chang, Hwai Wen, Vogt, Peter K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC218767/
https://ncbi.nlm.nih.gov/pubmed/14530393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135336100
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