DcpS can act in the 5′–3′ mRNA decay pathway in addition to the 3′–5′ pathway
Eukaryotic mRNA degradation proceeds through two main pathways, both involving mRNA cap breakdown. In the 3′–5′ mRNA decay pathway, mRNA body degradation generates free m7GpppN that is hydrolyzed by DcpS generating m7GMP. In the 5′–3′ pathway, the recently identified human Dcp2 decapping enzyme clea...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14523240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1635192100 |
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