DcpS can act in the 5′–3′ mRNA decay pathway in addition to the 3′–5′ pathway
Eukaryotic mRNA degradation proceeds through two main pathways, both involving mRNA cap breakdown. In the 3′–5′ mRNA decay pathway, mRNA body degradation generates free m7GpppN that is hydrolyzed by DcpS generating m7GMP. In the 5′–3′ pathway, the recently identified human Dcp2 decapping enzyme clea...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14523240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1635192100 |
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