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3D structure of Syk kinase determined by single particle electron microscopy

The cytoplasmic Syk kinase plays key roles in immune responses and comprises two N-terminal regulatory Src homology 2 (SH2) domains followed by a catalytic region. Atomic structures of these domains have only been solved in isolation. To gain insights into the three-dimensional structure of full-len...

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Hlavní autoři: Arias-Palomo, Ernesto, Recuero-Checa, María A., Bustelo, Xosé R., Llorca, Oscar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186377/
https://ncbi.nlm.nih.gov/pubmed/18021750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2007.10.008
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