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3D structure of Syk kinase determined by single particle electron microscopy
The cytoplasmic Syk kinase plays key roles in immune responses and comprises two N-terminal regulatory Src homology 2 (SH2) domains followed by a catalytic region. Atomic structures of these domains have only been solved in isolation. To gain insights into the three-dimensional structure of full-len...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2186377/ https://ncbi.nlm.nih.gov/pubmed/18021750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2007.10.008 |
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