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NITRIC OXIDE-DEPENDENT PROTEASOMAL DEGRADATION OF CYTOCHROME P450 2B PROTEINS

Exposure to inflammatory agents or cytokines causes the suppression of cytochrome P450 (CYP) enzyme activities and expression in liver and primary hepatocyte cultures. We showed previously that phenobarbital-induced CYP2B protein is down-regulated in primary cultures of rat hepatocytes following exp...

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Detalhes bibliográficos
Main Authors: Lee, Choon-Myung, Kim, Bong-Yoon, Li, Lian, Morgan, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185771/
https://ncbi.nlm.nih.gov/pubmed/17993647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708821200
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