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Regulation of Cytochrome P450 enzyme activity and expression by Nitric Oxide in the context of inflammatory disease

Many hepatic cytochrome P450 enzymes and their associated drug metabolizing activities are down-regulated in disease states, and much of this has been associated with inflammatory cytokines and their signaling pathways. One such pathway is the induction of inducible nitric oxide synthase (NOS2) and...

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Detalhes bibliográficos
Publicado no:Drug Metab Rev
Main Authors: Morgan, Edward T., Skubic, Cene, Lee, Choon-myung, Cokan, Kaja Blagotinšek, Rozman, Damjana
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709541/
https://ncbi.nlm.nih.gov/pubmed/32898444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602532.2020.1817061
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