A carregar...

Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells

Several cytochrome P450 enzymes are known to be down-regulated by nitric oxide (NO). CYP2A6 is responsible for the metabolism of nicotine and several other xenobiotics, but its susceptibility to down-regulation by NO has not been reported. To address this question, we used Huh7 human hepatoma cell l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Cerrone, John, Lee, Choon-myung, Mi, Tian, Morgan, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289052/
https://ncbi.nlm.nih.gov/pubmed/32350062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.089961
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!