Plaque-induced neurite abnormalities: Implications for disruption of neural networks in Alzheimer’s disease

The brains of Alzheimer’s disease patients contain extracellular Aβ amyloid deposits (senile plaques). Although genetic evidence causally links Aβ deposition to the disease, the mechanism by which Aβ disrupts cortical function is unknown. Using triple immunofluorescent confocal microscopy and three-...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Knowles, Roger B., Wyart, Claire, Buldyrev, Sergey V., Cruz, Luis, Urbanc, Brigita, Hasselmo, Michael E., Stanley, H. Eugene, Hyman, Bradley T.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1999
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5274
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