Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).

The discovery that the epsilon 4 allele of the apolipoprotein E (apoE) gene is a putative risk factor for Alzheimer disease (AD) in the general population has highlighted the role of genetic influences in this extremely common and disabling illness. It has long been recognized that another genetic a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hyman, B T, West, H L, Rebeck, G W, Buldyrev, S V, Mantegna, R N, Ukleja, M, Havlin, S, Stanley, H E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3586
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