Plaque-induced neurite abnormalities: Implications for disruption of neural networks in Alzheimer’s disease

The brains of Alzheimer’s disease patients contain extracellular Aβ amyloid deposits (senile plaques). Although genetic evidence causally links Aβ deposition to the disease, the mechanism by which Aβ disrupts cortical function is unknown. Using triple immunofluorescent confocal microscopy and three-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Knowles, Roger B., Wyart, Claire, Buldyrev, Sergey V., Cruz, Luis, Urbanc, Brigita, Hasselmo, Michael E., Stanley, H. Eugene, Hyman, Bradley T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5274
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