High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum

Recently, hptc, a human gene homologous to the Drosophila segment polarity gene patched (ptc), has been implicated in the nevoid basal-cell carcinoma (BCC) syndrome, and somatic mutations of hptc also have been found in sporadic BCCs, the most frequent cancers found in the white population. We have...

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Hlavní autoři: Bodak, Nathalie, Queille, Sophie, Avril, Marie Françoise, Bouadjar, Bakar, Drougard, Christiane, Sarasin, Alain, Daya-Grosjean, Leela
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC21826/
https://ncbi.nlm.nih.gov/pubmed/10220428
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