High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum

Recently, hptc, a human gene homologous to the Drosophila segment polarity gene patched (ptc), has been implicated in the nevoid basal-cell carcinoma (BCC) syndrome, and somatic mutations of hptc also have been found in sporadic BCCs, the most frequent cancers found in the white population. We have...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bodak, Nathalie, Queille, Sophie, Avril, Marie Françoise, Bouadjar, Bakar, Drougard, Christiane, Sarasin, Alain, Daya-Grosjean, Leela
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5117
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