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The intracellular domain of interferon-α receptor 2c (IFN-αR2c) chain is responsible for Stat activation
Type I IFNs activate the Jak–Stat signal transduction pathway. The IFN-α receptor 1 (IFN-αR1) subunit and two splice variants of the IFN-αR2 subunit, IFN-αR2c and IFN-αR2b, are involved in ligand binding. All these receptors have been implicated in cytokine signaling and, specifically, in Stat recru...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21807/ https://ncbi.nlm.nih.gov/pubmed/10220409 |
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