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Cisplatin nephrotoxicity: molecular mechanisms

Cisplatin is one of the most widely used chemotherapeutic agents for the treatment of several human malignancies. The efficacy of cisplatin is dose dependent, but the significant risk of nephrotoxicity frequently hinders the use of higher doses to maximize its antineoplastic effects. Several advance...

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Detalhes bibliográficos
Main Authors: Hanigan, Marie H., Devarajan, Prasad
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180401/
https://ncbi.nlm.nih.gov/pubmed/18185852
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