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Cisplatin nephrotoxicity: molecular mechanisms

Cisplatin is one of the most widely used chemotherapeutic agents for the treatment of several human malignancies. The efficacy of cisplatin is dose dependent, but the significant risk of nephrotoxicity frequently hinders the use of higher doses to maximize its antineoplastic effects. Several advance...

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Bibliographic Details
Main Authors: Hanigan, Marie H., Devarajan, Prasad
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180401/
https://ncbi.nlm.nih.gov/pubmed/18185852
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