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Role of Glutathione S-Transferase Pi in Cisplatin Induced Nephrotoxicity
One of the dose-limiting toxicities of cisplatin is nephrotoxicity. Renal toxicity is localized to quiescent proximal tubule cells, where the formation of DNA-adducts cannot account for the dose-limiting toxicity. Our earlier results have shown that a glutathione-conjugate of cisplatin is metabolize...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667699/ https://ncbi.nlm.nih.gov/pubmed/18819770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2008.08.004 |
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