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Neuroendocrine tumor cell growth inhibition by ZM336372 through alterations in multiple signaling pathways

BACKGROUND: We have previously shown that activation of the Raf-1/MEK/ERK1/2 signaling pathway by ZM336372 inhibits carcinoid cells growth. In the present study, we further characterize the molecular details of the growth inhibition by the signaling-based compound ZM336372 in neuroendocrine tumors (...

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Detalhes bibliográficos
Main Authors: Kunnimalaiyaan, Muthusamy, Ndiaye, Mary, Chen, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180346/
https://ncbi.nlm.nih.gov/pubmed/18063082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2007.09.020
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