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ZM336372 Induces Apoptosis Associated With Phosphorylation of GSK-3β in Pancreatic Adenocarcinoma Cell Lines
INTRODUCTION: ZM336372 is small molecule tyrosine kinase modulator. It has been shown to inhibit glycogen synthase kinase-3β (GSK-3β) through phosphorylation of GSK-3β at Ser 9. GSK-3β has previously been shown to mediate cell survival in pancreatic cancer cells. Here we determine the effects of ZM3...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379885/ https://ncbi.nlm.nih.gov/pubmed/20031160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2009.06.013 |
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