Antiproliferative and apoptotic effect of LY2090314, a GSK-3 inhibitor, in neuroblastoma in vitro

BACKGROUND: Neuroblastoma (NB) is a devastating disease. Despite recent advances in the treatment of NB, about 60% of high-risk NB will have relapse and therefore long-term event free survival is very minimal. We have reported that targeting glycogen synthase kinase-3 (GSK-3) may be a potential stra...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Kunnimalaiyaan, Selvi, Schwartz, Victoriana K., Jackson, Iris Alao, Clark Gamblin, T., Kunnimalaiyaan, Muthusamy
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948712/
https://ncbi.nlm.nih.gov/pubmed/29751783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4474-7
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