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Neuroendocrine phenotypic alteration and growth suppression through apoptosis by MK-2206, an allosteric AKT inhibitor, in carcinoids
Carcinoids are neuroendocrine malignancies, often characterized by their potential to hypersecrete bioactive hormones that contribute to the carcinoid syndrome. Previously, we reported that AKT serves as a central regulator of carcinoid growth and phenotypic expression, demonstrated by genetic silen...
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| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510354/ https://ncbi.nlm.nih.gov/pubmed/23147412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e3283584f75 |
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