Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide

BACKGROUND: Using a human small cell lung cancer (SCLC) xenografted in nude mice, we have previously reported enhanced tumor growth inhibition following chemotherapy in combination with imatinib (STI571). We therefore investigated the in vivo impact of imatinib on the pharmacokinetics and efficacy o...

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Detalhes bibliográficos
Main Authors: Rezaï, Keyvan, Lokiec, François, Grandjean, Isabelle, Weill, Sophie, de Cremoux, Patricia, Bordier, Vincent, Ekue, Richard, Garcia, Mickael, Poupon, Marie-France, Decaudin, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180168/
https://ncbi.nlm.nih.gov/pubmed/17963518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-7-13
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