Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide

BACKGROUND: Using a human small cell lung cancer (SCLC) xenografted in nude mice, we have previously reported enhanced tumor growth inhibition following chemotherapy in combination with imatinib (STI571). We therefore investigated the in vivo impact of imatinib on the pharmacokinetics and efficacy o...

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Main Authors: Rezaï, Keyvan, Lokiec, François, Grandjean, Isabelle, Weill, Sophie, de Cremoux, Patricia, Bordier, Vincent, Ekue, Richard, Garcia, Mickael, Poupon, Marie-France, Decaudin, Didier
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180168/
https://ncbi.nlm.nih.gov/pubmed/17963518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-7-13
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